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Associate Professor, University of Chicago Pritzker School of Medicine

A mere proposal to promote or facilitate the prostitution or corruption of a person under age is already a consummation of the crime blood pressure explained generic trandate 100 mg visa. The term under age presumably means below the age of 18 blood pressure vs pulse pressure discount trandate line, inasmuch as 18 blood pressure on apple watch trandate 100 mg online, insofar as sexual offenses are concerned blood pressure essentials buy cheap trandate on-line, is the age of legal consent. Any one of the above mentioned act is sufficient to constitute offense which need not be habitual. Upon any public officer who shall solicit or make immoral or indecent advances to a woman interested in matters pending before such officer for decision, or with respect to which he is requested to submit a report to , or consult with, a superior officer; 2. Any warden or other public officer directly charged with the care and custody of prisoner or persons under arrest who shall solicit or make immoral or indecent advances to a woman under his custody. If a person solicited by the wife, daughter, sister or relative within the same degree by affinity of any person in the custody of such warden or officer, the penalties shall be prision correccional in its minimum and medium periods and temporary special disqualification. By soliciting or making immoral or indecent advances to a woman interested in matters pending before the offending officer for decision or with respect to which he is required to submit a report to , or consult with a superior officer. By soliciting or making immoral or indecent advances to the wife, daughter or relatives with the same degree by affinity of any person in custody of the offending warden or officer. Solicit means to propose earnestly and persistently something immoral or indecent. It is not necessary that the woman solicited yields to the solicitation of the offender. But proof of solicitation may no longer be necessary when there is sexual intercourse. Absence of sufficient solicitation is not necessary when the act solicited was consumated (U. There is no specific provision of our Revised Penal Code on any of the unnatural sexual offenses, although certain provisions of the code may be made applicable. Municipal ordinances of cities and towns may penalize unnatural sexual offenses in consonance with the power to promulgate rules and regulations necessary for the promotion of public safety, moral and welfare. Provisions of the Penal Code which may be Applicable to Unnatural Sexual Offenses: 1. Such act or acts is/are highly scandalous and offending against decency and good customs; c. It is also necessary that the act or acts be committed in a public place or within the view or knowledge of the public (U. Those who shall publicly expound or proclaim doctrines openly contrary to public morals; b. The authors of obscene literature, published with their knowledge in any form, and the editors publishing such literature; c. Those who in theaters, fairs, cinematographs or any other place open to public view, shall exhibit indecent or immoral plays, scenes, acts or shows; and d. Those who shall sell, give away or exhibit prints, engravings, sculptures or literature which are offensive to morals. For the purposes of this article, women who, for money or profit, habitually indulge in sexual intercourse or lascivious conduct, are deemed to be prostitutes. Any person found guilty of any of the offenses covered by this article shall be punished by arresto mayor or a fine not exceeding 200 pesos, and in case of recidivism, by arresto mayor in its medium period to prision correccional in its minimum period or a fine ranging from 200 to 2,000 pesos, or both, in the discretion of the court. Unjust vexation includes any human conduct, although not productive of some physical or material harm would, however, unjustly annoy of vex an innocent person (Guevarra). Homosexual - (Michaelangelo, Shakespeare, Oscar Wilde, Waltz Whiteman), - Sexual desire towards the same sex. Kinds of Homosexuals: (1) Overt - Persons who are conscious of their homosexual cravings, and who make no attempts to disguise their intention. Tribadism (Lesbianism) - A special name for female homosexuals wherein a woman has the desire to have sexual intercourse with another woman. Pedophilia - A form of sexual perversion wherein a person has the compulsive desire to have sexual intercourse with a child of either sex.

In addition blood pressure of 140 90 100 mg trandate for sale, our employees are employed at-will heart attack neck pain buy genuine trandate, which means that any of our employees could leave our employment at any time blood pressure medication new zealand buy generic trandate 100mg line, with or without notice blood pressure chart standing buy discount trandate 100 mg online. If we are unable to attract, incentivize and retain quality personnel on acceptable terms, or at all, it may seriously harm our business. We will need to grow the size and capabilities of our organization, and we may experience difficulties in managing this growth. As our development plans and strategies develop, and as we transition into operating as a public company, we must add a significant number of additional managerial, operational, financial and other personnel. Our future financial performance and our ability to continue to develop and, if approved, commercialize our product candidates will depend, in part, on our ability to effectively manage any future growth. Our management may also have to divert a disproportionate amount of its attention away from day-to-day activities in order to manage these growth activities. We currently rely, and for the foreseeable future will continue to rely, in substantial part on certain independent organizations, advisors and consultants to provide certain services. Please Consider the Environment Before Printing this Document Table of Contents assurance that the services of these independent organizations, advisors and consultants will continue to be available to us on a timely basis when needed, or that we can find qualified replacements. In addition, if we are unable to effectively manage our outsourced activities or if the quality or accuracy of the services provided by consultants is compromised for any reason, our clinical trials may be extended, delayed, or terminated, and we may not be able to obtain regulatory approval of our product candidates or otherwise advance our business. There can be no assurance that we will be able to manage our existing consultants or find other competent outside contractors and consultants on economically reasonable terms, if at all. If we are not able to effectively expand our organization by hiring new employees and expanding our groups of consultants and contractors, we may not be able to successfully implement the tasks necessary to further develop our product candidates and, accordingly, may not achieve our research, development and commercialization goals. Unfavorable global economic conditions could adversely affect our business, financial condition or results of operations. Our results of operations could be adversely affected by general conditions in the global economy and in the global financial markets. Portions of our future clinical trials may be conducted outside of the United States and unfavorable economic conditions resulting in the weakening of the U. Furthermore, the most recent global financial crisis caused extreme volatility and disruptions in the capital and credit markets. A severe or prolonged economic downturn could result in a variety of risks to our business, including a reduced ability to raise additional capital when needed on acceptable terms, if at all. A weak or declining economy or international trade disputes could also strain our suppliers, some of which are located outside of the United States, possibly resulting in supply disruption. Any of the foregoing could harm our business and we cannot anticipate all of the ways in which the current economic climate and financial market conditions could adversely impact our business. The estimates of market opportunity and forecasts of market growth included in this prospectus may prove to be inaccurate, and even if the markets in which we compete achieve the forecasted growth, our business may not grow at similar rates, or at all. Market opportunity estimates and growth forecasts included in this prospectus are subject to significant uncertainty and are based on assumptions and estimates which may not prove to be accurate. The estimates and forecasts included in this prospectus relating to size and expected growth of our target market may prove to be inaccurate. Even if the markets in which we compete meet the size estimates and growth forecasts included in this prospectus, our business may not grow at similar rates, or at all. Our growth is subject to many factors, including our success in implementing our business strategy, which is subject to many risks and uncertainties. If we engage in acquisitions or strategic partnerships, this may increase our capital requirements, dilute our stockholders, cause us to incur debt or assume contingent liabilities and subject us to other risks. We may engage in various acquisitions and strategic partnerships in the future, including licensing or acquiring complementary products, intellectual property rights, technologies or businesses. Please Consider the Environment Before Printing this Document Table of Contents assimilation of operations, intellectual property, products and product candidates of an acquired company, including difficulties associated with integrating new personnel; the diversion of our managements attention from our existing product candidates and initiatives in pursuing such an acquisition or strategic partnership; retention of key employees, the loss of key personnel, and uncertainties in our ability to maintain key business relationships; risks and uncertainties associated with the other party to such a transaction, including the prospects of that party and their existing products or product candidates and regulatory approvals; and our inability to generate revenue from acquired intellectual property, technology and/or products sufficient to meet our objectives or even to offset the associated transaction and maintenance costs. In addition, if we undertake such a transaction, we may incur large one-time expenses and acquire intangible assets that could result in significant future amortization expense. In September 2019, we experienced a phishing attack in which the email account of a single non-officer employee was compromised. Our security controls detected the compromise, and we were able to block the unauthorized access, but not before the attacker was able to use the account to send out additional phishing emails. We do not believe the phishing attack was a material incursion because, among other reasons, none of our data was accessed or compromised, and we have not incurred any related material remediation costs.

Fracture of Bones and Course in Visceral Organs: Occasionally arteriosclerosis obliterans cheap trandate 100mg otc, the nature of the bone fracture may show the direction prehypertension cdc buy trandate 100mg, especially when the bullet is not deformed before causing the fracture blood pressure medication helps ed generic trandate 100mg fast delivery. Injuries in solid visceral organs may clearly manifest the course because of the absence of contractility blood pressure chart print out quality trandate 100 mg. Location of Bone Fragments and Lead Particles: 361 the bone spicules and lead fragments go with the flight of the bullet and may be utilized in the determination of the trajectory. X-ray Examination: Bone spicules and lead fragments may be observed and their exact location determined in relation with the wound of entrance. Relative difference in the vertical location of the entrance from the exit in the clothings. Relative position and distance of the assailant from the victim in the reconstruction or reenactment of the crime. Exit (Outshoot) Wound: ^ An exit wound does not show characteristic shape unlike the wound of entrance. It may be slit-like, stellate, irregular or even similar to the wound of entrance. This is due to the absence of external support beyond the skin so the bullet tends to tear or shatter the skin while sufficient amount of kinetic energy is still in the bullet during the process of piercing the skin. Aside from the bone, the skin is one of the most resistant to penetrate in the course of the bullet so that most often the bullet is lodged just underneath the skin. It may only be noticed by the presence of contusion over the area wherein it is lodged or its presence may be noticed by palpitation. The bullet may have lost its^monierj^um after piercing the skin and just fall without perforation of the clothing. Bones may be involved in the trajectory and its spicules may create additional injury to the wound of exit. Variation on the shape of the wound of exit may be attributable to the deformity of the bullet in its passage in the body and to the wabbling and stumbling movement of the bullet during its course and fragmentation of the missiles. Shored Gunshot Wound of Exit - If the place where the gunshot wound of exit is pressed on a hard pbject as when the victim is lying on his back on a hard object or in small caliber shots (like 0. Shored gunshot wound of exit is produced when the outstretched skin is impaled, sandwiched and crushed between the outgoing bullet and the unyielding object is over the exit site, thus making the wound to be circular with abrasion collar at its margin. Proper coaptation of the wound margin is impossible because of the loss of skin just like those observed in entrance wound. In contrast with the entrance wound, the supported exit wound shows a scalloped or punched-out abrasion collar and sharply contoured skin in between the radiating skin lacerations marginating the abrasion (Journal of Forensic Medicine and Pathology, Vol. G u n s h o t w o u n d o f exit o f the skull w i t h p u n c h out edges stinction Between Gunshot Wound of Entrance and Wound of Exit: Entrance Wound 1. The "Odd and Even Rule" in Gunshot Wounds: ^ If the number of gunshot wounds of entrance and exit found in the body of the victim is even, the presumption is that no bullet is lodged in the body, but if the number of the gunshot wounds of entrance and exit is odd, the presumption is that one or more bullets might have been lodged in the body. The rule is merely presumptive and actual inspection and autopsy will verify the truth of the presumption. It may be possible that all of those wounds or a majority of them are entrance wounds with some bullets lodged, yet the number may still be even. Sometimes it is difficult to locate the lodged bullet but with the help of a portable X-ray, its location and extraction can be facilitated. Determination of the Number of Spent Shells: Search must be made at the scene of the crime or at the place where the offender made the fire, for spent shells, if the weapon used is an automatic pistol or rifle. In case of revolver fire, the empty shells may be found still inside the cylindrical magazine. In machine gun fire, the spent shells may still be attached to the cartridge belt. Determination of Entrance Wounds in the Body of the Victim: Although most often erroneous, the investigator may be given an idea as to the minimum number of shots made. The number of wounds of entrance may not show the exact number of fire because: a.

The later sections of this chapter describe disorders of the reproductive systems blood pressure chart low purchase trandate 100mg on-line. Female reproductive system Learning outcomes After studying this section prehypertension pregnancy order trandate 100mg with visa, you should be able to: describe the main structures of the external genitalia explain the structure and function of the vagina describe the location pulse pressure 81 buy generic trandate 100 mg line, structure and function of the uterus and the uterine tubes discuss the process of ovulation and the hormones that control it outline the changes that occur in the female at puberty arteria carotida interna quality trandate 100mg, including the physiology of menstruation describe the structure and function of the female breast. The female reproductive organs, or genitalia, include both external and internal organs. They are composed of skin, fibrous tissue and fat and contain large numbers of sebaceous glands. Anteriorly the folds join in front of the symphysis pubis, and posteriorly they merge with the skin of the perineum. At puberty, hair grows on the mons pubis and on the lateral surfaces of the labia majora. Labia minora these are two smaller folds of skin between the labia majora, containing numerous sebaceous glands. The vagina, urethra and ducts of the greater vestibular glands open into the vestibule. Clitoris the clitoris corresponds to the penis in the male and contains sensory nerve endings and erectile tissue, but it has no reproductive significance. Hymen the hymen is a thin layer of mucous membrane that partially occludes the opening of the vagina. They are about the size of a small pea and have ducts, opening into the vestibule immediately lateral to the attachment of the hymen. Blood supply, lymph drainage and nerve supply Arterial supply this is by branches from the internal pudendal arteries that branch from the internal iliac arteries and by external pudendal arteries that branch from the femoral arteries. Venous drainage this forms a large plexus which eventually drains into the internal iliac veins. Perineum the perineum is the area extending from the base of the labia minora to the anal canal. Internal genitalia the internal organs of the female reproductive system (Figs 18. Vagina the vagina is a fibromuscular tube lined with stratified squamous epithelium. The difference is due to the angle of insertion of the cervix through the anterior wall. Structure of the vagina the vagina has three layers: an outer covering of areolar tissue, a middle layer of smooth muscle and an inner lining of stratified squamous epithelium that forms ridges or rugae. Between puberty and the menopause, Lactobacillus acidophilus bacteria are normally present, which secrete lactic acid, maintaining the pH between 4. The acidity inhibits the growth of most other micro-organisms that may enter the vagina from the perineum. Blood supply, lymph drainage and nerve supply Arterial supply An arterial plexus is formed round the vagina, derived from the uterine and vaginal arteries, which are branches of the internal iliac arteries. Venous drainage A venous plexus, situated in the muscular wall, drains into the internal iliac veins. Nerve supply this consists of parasympathetic fibres from the sacral outflow, sympathetic fibres from the lumbar outflow and somatic sensory fibres from the pudendal nerves. Functions of the vagina the vagina acts as the receptacle for the penis during sexual intercourse (coitus), and provides an elastic passageway through which the baby passes during childbirth. Uterus the uterus is a hollow muscular pear-shaped organ, flattened anteroposteriorly. In most women, it leans forward (anteversion), and is bent forward (anteflexion) almost at right angles to the vagina, so that its anterior wall rests partly against the bladder below, and forming the vesicouterine pouch between the two organs. Fundus this is the dome-shaped part of the uterus above the openings of the uterine tubes.

New bone forms as large numbers of osteoblasts secrete spongy bone heart attack xbox order trandate 100mg free shipping, which unites the broken ends blood pressure chart heart foundation cheap trandate online, and is protected by an outer layer of bone and cartilage; these new deposits of bone and cartilage are called callus blood pressure medication urination purchase trandate 100 mg with mastercard. Over the next few weeks hypertension jnc8 purchase trandate from india, the callus matures, and the cartilage is gradually replaced with new bone. Reshaping of the bone continues and gradually the medullary canal is reopened through the callus (in weeks or months). In time the bone heals completely with the callus tissue completely replaced with mature compact bone. Often the bone is thicker and stronger at the repair site than originally, and a second fracture is more likely to occur at a different site. Factors that delay healing of fractures Tissue fragments between bone ends Splinters of dead bone (sequestrae) and soft tissue fragments not removed by phagocytosis delay healing. Deficient blood supply this delays growth of granulation tissue and new blood vessels. Hypoxia also reduces the number of osteoblasts and increases the number of chondrocytes that develop from their common parent cells. This may lead to cartilaginous union of the fracture, which results in a weaker repair. The most vulnerable sites, because of their normally poor blood supply, are the neck of femur, the scaphoid and the shaft of tibia. Poor alignment of bone ends this may result in the formation of a large and irregular callus that heals slowly and often results in permanent disability. Continued mobility of bone ends Continuous movement results in fibrosis of the granulation tissue followed by fibrous union of the fracture. Miscellaneous these include: infection (see below) systemic illness malnutrition drugs. Fat embolism Emboli consisting of fat from the marrow in the medullary canal may enter the circulation through torn veins. They are most likely to lodge in the lungs and block blood flow through the pulmonary capillaries. Axial skeleton Learning outcomes After studying this section you should be able to: identify the bones of the skull (face and cranium) list the functions of the sinuses and fontanelles of the skull outline the characteristics of a typical vertebra describe the structure of the vertebral column explain the movements and functions of the vertebral column identify the bones forming the thoracic cage. The bones of the skeleton are divided into two groups: the axial skeleton and the appendicular skeleton. Together the bones forming these structures constitute the central bony core of the body, the axis. Cranium the cranium is formed by a number of flat and irregular bones that provide a bony protection for the brain. It has a base upon which the brain rests and a vault that surrounds and covers it. The periosteum lining the inner surface of the skull bones forms the outer layer of dura mater. In the mature skull the joints (sutures) between the bones are immovable (fibrous). The bones of the cranium are: 1 frontal bone 2 parietal bones 2 temporal bones 1 occipital bone 1 sphenoid bone 1 ethmoid bone. It forms part of the orbital cavities (eye sockets) and the prominent ridges above the eyes, the supraorbital margins. Just above the supraorbital margins, within the bone, are two air-filled cavities or sinuses lined with ciliated mucous membrane, which open into the nasal cavity. The coronal suture joins the frontal and parietal bones and other fibrous joints are formed with the sphenoid, zygomatic, lacrimal, nasal and ethmoid bones. The bone originates in two parts joined in the midline by the frontal suture. They articulate with each other at the sagittal suture, with the frontal bone at the coronal suture, with the occipital bone at the lambdoidal suture and with the temporal bones at the squamous sutures. The inner surface is concave and is grooved to accommodate the brain and blood vessels.

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